HoLEP vs TURP for Enlarged Prostate

January 29, 2019



HoLEP vs TURP is one comparison that men with benign prostatic hyperplasia (BPH) might make when deciding on a treatment for their enlarged prostate. Gradual enlargement of the prostate is a noncancerous condition that can partially or completely obstruct urine flow. Holmium laser enucleation of the prostate (HoLEP) and Transurethral resection of the prostate (TURP) are two common procedures for BPH.

HoLEP is a newer procedure for the transurethral removal of a prostate weighing more than 100 g (about 3.5 oz.). Transurethral resection of the prostate (TURP) is a surgical procedure that has been around for more than a century, since 1901.

According to Johns Hopkins Health Alerts, a recent study published in BJU International found that HoLEP has better long-term results than TURP as well as some other positive results. For the study, researchers followed up with 31 of 61 men who had participated in an earlier evaluation that compared HoLEP vs TURP. Fourteen of the men in the follow-up study had been treated with HoLEP and seventeen with TURP.

Results of HoLEP vs TURP

The HoLEP procedure is considered a minimally invasive alternative to TURP for treatment of BPH. On average during the 7.6 years, virtually no men in the HoLEP group needed to repeat the procedure, compared with three men having to repeat in the TURP group. Men who received HoLEP had less time using a catheter and reported shorter hospital stays and minimal blood loss. Side effects and symptoms after the first year were similar between the two groups, and both procedures caused retrograde ejaculation, or dry climax.


Additional studies have also found shorter catheterization times and hospital stays with patients who received HoLEP. The finding that HoLEP patients did not require retreatment provides further evidence that some men may find HoLEP to be an appropriate and effective alternative to TURP. The National Institutes of Health claims that HoLEP provides “the ideal combination of cutting and coagulation.”

Regarding HoLEP vs TURP, you should talk to your doctor to see which procedure is best for your condition. Be sure to research your surgeon’s level of training and experience before having the procedure. It is always important to make sure you thoroughly understand the potential benefits and risks of any procedure. All of these factors can help you decide on HoLEP vs TURP.