A Peyronie’s disease cure often may not be necessary because some cases just require monitoring and no treatment during the initial stages. Not all cases of Peyronie’s disease need treatment. In fact, some men experience a spontaneous recovery from Peyronie’s disease, although no one has identified why this happens.
In mild cases of Peyronie’s disease, doctors will often recommend not attempting treatment. For example, men who have little or no loss of rigidity in their penis or who have minimal curvature and/or pain and whose sexual function is not affected do not need treatment. In fact, men with such symptoms should be discouraged from treatment, because they are unlikely to get any benefit from it, and they also risk the chance of worsening symptoms they already have.
If symptoms get worse during the watch and wait period, however, then men need to consult their physician and reconsider treatment.
How often does Peyronie’s disease cure without treatment? This question was addressed in an analysis of 246 men who were seen within 6 months of the start of symptoms and then observed for at least 12 months, during which time they did not receive treatment. The mean penile curvature at the start of the study was 42 degrees. By the end of follow-up, 12% of the men had improved (a change of 15 degrees), 40% had no Peyronie’s disease cure, and 48% got worse (mean change of 22 degrees).
All the men who had pain when they entered the study said the pain had improved by the end of follow-up, and 89% reported it had gone away completely without treatment. (Mulhall) Typically, Peyronie’s disease is painful during the first six months, after which the pain dissipates on its own.
Mulhall JP et al. An analysis of the natural history of Peyronie’s disease. J Urol Jun 2006; 175(6):2115-18