The side effects of Jalyn may be concerning to men who take this prescription drug for BPH symptoms. Jalyn is a combination of two medications that each treat BPH in a different way: tamsulosin (Flomax) and dutasteride (Avodart). Tamsulosin relaxes the muscles in the prostate and bladder neck, which makes it easier to urinate. Dutasteride is a 5-alpha-reductase inhibitor that treats symptoms of BPH by slowing the growth of the prostate. Dutasteride also can help reduce the size of the prostate by blocking the conversion of testosterone to dihydrotestosterone (DHT), a hormone that stimulates prostate growth. As the prostate shrinks over time, urinary tract symptoms can resolve.
Men who take Jalyn may experience adverse reactions that are similar to the Flomax side effects and Avodart side effects individually.
Jalyn side effects may include:
- Postural hypotension
- Stuffy or runny nose
- Erectile dysfunction
- Reduce sperm count, semen volume, and sperm movement
- Loss of libido
- Painful erection that can last over four hours
- Breast enlargement and tenderness
- Ejaculation problems
- Abnormal orgasm
- Risk of high-grade prostate cancer
If you experience the painful erection side effect, treat it as a medical emergency and seek medical help. It could lead to permanent problems if not treated.
Jalyn was approved by the Food and Drug Administration (FDA) in June 2010. It is a pill taken once a day. Results of clinical trials of Jalyn (0.5 mg dutasteride, 0.4 mg tamsulosin) showed that men who used the drug experienced significantly better relief of BPH symptoms than did men who took the same amount of either Flomax or Avodart alone.
Other safety warnings
In 2011, the FDA issued a safety warning regarding an increased risk of high-grade prostate cancer associated with the use of 5-alpha-reductase inhibitors, including Avodart, Jalyn, Proscar, and Propecia (the latter two are forms of finasteride). All of these drugs now have a warning box on their labels indicating this increased risk.
Jalyn side effects can have a significant impact on the lives of men who use this drug. Before starting this medication, be sure to discuss the benefits and risks with your healthcare provider. Make sure your doctor and pharmacist have a complete list of all the medications you take. The drugs that make up Jalyn can have bad interactions with other medications.